{"id":4051,"date":"2026-07-31T23:46:30","date_gmt":"2026-08-01T02:46:30","guid":{"rendered":"https:\/\/hiox.com.ar\/hiox\/los-antecedentes-familiares-juegan-un-papel-en-el-riesgo-genetico-de-cancer-de-mama-segun-los-investigadores\/"},"modified":"2026-07-31T23:46:30","modified_gmt":"2026-08-01T02:46:30","slug":"los-antecedentes-familiares-juegan-un-papel-en-el-riesgo-genetico-de-cancer-de-mama-segun-los-investigadores","status":"publish","type":"post","link":"https:\/\/hiox.com.ar\/hiox\/los-antecedentes-familiares-juegan-un-papel-en-el-riesgo-genetico-de-cancer-de-mama-segun-los-investigadores\/","title":{"rendered":"Los antecedentes familiares juegan un papel en el riesgo gen\u00e9tico de c\u00e1ncer de mama, seg\u00fan los investigadores"},"content":{"rendered":"<p>Informaci\u00f3n detallada sobre <strong>Los antecedentes familiares juegan un papel en el riesgo gen\u00e9tico de c\u00e1ncer de mama, seg\u00fan los investigadores<\/strong>. Te traemos las \u00faltimas noticias sobre Noticia Infobae, un tema de gran inter\u00e9s para hoy 31 July, 2026.<\/p>\n<div class=\"entry-content-body\">\n<div><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.infobae.com\/resizer\/v2\/K4PAIDZB7ZGNVLOEQZRBBKSS2I.jpg?auth=961dd0740a67da121a3b79488b19a011b7fc1721502c95c604204eefd7fd85dd&amp;smart=true&amp;width=1200&amp;height=801\" alt=\"\" height=\"801\" width=\"1200\"><\/p>\n<p>VIERNES, 31 de julio de 2026 (HealthDay News) &#8212; El riesgo gen\u00e9tico de c\u00e1ncer de mama de una mujer depende tanto de su historial familiar como de la presencia de mutaciones causantes de c\u00e1ncer, seg\u00fan un nuevo estudio.<\/p>\n<p>El riesgo de c\u00e1ncer de mama entre las mujeres evaluadas por mutaciones en el gen BRCA vari\u00f3 seg\u00fan el historial de c\u00e1ncer de los familiares, informaron los investigadores el 30 de julio en JAMA Network Open.<\/p>\n<p>Entre las mujeres que dieron positivo en una mutaci\u00f3n BRCA, el riesgo de c\u00e1ncer de mama vari\u00f3 entre aproximadamente el 56% y el 86%, dependiendo del n\u00famero de familiares directos que tuvieran c\u00e1ncer de mama u ovario, seg\u00fan encontraron los investigadores.<\/p>\n<p>\u00abBas\u00e1ndose en estos hallazgos, un m\u00e9dico podr\u00eda recomendar mamograf\u00edas o resonancias magn\u00e9ticas de mama m\u00e1s frecuentes a una paciente positiva para BRCA en sus 50 o 60 a\u00f1os sin antecedentes familiares de c\u00e1ncer de mama, pero sugerir la mastectom\u00eda preventiva como opci\u00f3n para una paciente joven con BRCA y varios casos de c\u00e1ncer de mama en la familia\u00bb, dijo la investigadora principal , la Dra. Fahima Dossa , en un comunicado de prensa. Es onc\u00f3loga quir\u00fargica en el Cedars-Sinai Medical Center de Los \u00c1ngeles.<\/p>\n<p>Una mujer promedio tiene aproximadamente un 13% de probabilidad de desarrollar c\u00e1ncer de mama a lo largo de su vida, seg\u00fan los investigadores en notas de fondo.<\/p>\n<p>Las mujeres con mutaciones en BRCA1 o BRCA2 tienen un mayor riesgo de c\u00e1ncer de mama entre un 30% y un 70%, seg\u00fan los investigadores. Estas variantes interfieren con la capacidad del cuerpo para reparar da\u00f1os en el ADN que pueden derivar en c\u00e1ncer.<\/p>\n<p>Se recomienda la prueba BRCA para mujeres con antecedentes personales o familiares de ciertos tipos de c\u00e1ncer, una mutaci\u00f3n BRCA conocida en la familia o ascendencia jud\u00eda asquenaz\u00ed, seg\u00fan los investigadores.<\/p>\n<p>\u00abAunque la mayor\u00eda de las mujeres que se someten a pruebas gen\u00e9ticas no dan positivo en una mutaci\u00f3n BRCA que aumenta el riesgo de c\u00e1ncer, generalmente han sido derivadas a pruebas debido a un fuerte historial personal o familiar de c\u00e1ncer\u00bb, dijo Dossa.<\/p>\n<p>\u00abEl riesgo futuro de c\u00e1ncer para estas mujeres no ha sido bien estudiado, y nuestros hallazgos son los primeros en calcular ese riesgo para poder guiar mejor a todas las mujeres que se someten a la prueba BRCA\u00bb, afirm\u00f3.<\/p>\n<p>Para el estudio, los investigadores analizaron los historiales m\u00e9dicos de casi 16.000 mujeres que se sometieron a la prueba BRCA en Ontario, Canad\u00e1, entre 2007 y 2016.<\/p>\n<p>Los resultados tambi\u00e9n mostraron que las mujeres que dieron negativo en la prueba de mutaciones causantes de c\u00e1ncer en BRCA a\u00fan ten\u00edan un 25% de riesgo de por vida de desarrollar c\u00e1ncer de mama, probablemente debido a antecedentes familiares o ascendencia, seg\u00fan los investigadores.<\/p>\n<p>Del mismo modo, las mujeres con mutaciones BRCA que no se conoc\u00eda por estar relacionadas con el c\u00e1ncer de mama ten\u00edan un riesgo un 30% mayor de c\u00e1ncer de mama.<\/p>\n<p>Las \u00fanicas mujeres en el estudio con el mismo riesgo de c\u00e1ncer de mama que la poblaci\u00f3n general eran aquellas que ten\u00edan antecedentes familiares de c\u00e1ncer y una mutaci\u00f3n BRCA conocida en la familia, pero que no portaban esa mutaci\u00f3n espec\u00edfica, dijo Dossa.<\/p>\n<p>\u00abEste estudio es un recordatorio para los pacientes sobre la importancia de mantener conversaciones con sus m\u00e9dicos sobre los resultados de las pruebas gen\u00e9ticas\u00bb, afirm\u00f3. \u00abPor fin tenemos algunos datos para ayudar a informar esas conversaciones.\u00bb<\/p>\n<p>M\u00e1s informaci\u00f3n<\/p>\n<p>El Instituto Nacional del C\u00e1ncer tiene m\u00e1s informaci\u00f3n sobre las mutaciones BRCA y el c\u00e1ncer de mama.<\/p>\n<p>FUENTE: Cedars-Sinai Medical Center, comunicado de prensa, 30 de julio de 2026<\/p>\n<\/div>\n<\/div>\n<hr \/>\n<p>Esta noticia sobre <strong>Los antecedentes familiares juegan un papel en el riesgo gen\u00e9tico de c\u00e1ncer de mama, seg\u00fan los investigadores<\/strong> fue publicada originalmente en <a href=\"https:\/\/www.infobae.com\/arc\/outboundfeeds\/rss\/\" target=\"_blank\" rel=\"nofollow\">Infobae.com<\/a>. Puedes ampliar la informaci\u00f3n siguiendo el enlace a la fuente original: <a href=\"https:\/\/www.infobae.com\/salud\/2026\/08\/01\/los-antecedentes-familiares-juegan-un-papel-en-el-riesgo-genetico-de-cancer-de-mama-segun-los-investigadores\/\" target=\"_blank\" rel=\"noopener noreferrer\">Los antecedentes familiares juegan un papel en el riesgo gen\u00e9tico de c\u00e1ncer de mama, seg\u00fan los investigadores<\/a>.<\/p>\n<p><small>Categor\u00eda: Noticia Infobae | Fecha: 31 July, 2026<\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<div>Healthday Spanish<\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[23],"tags":[25,27,24,26],"class_list":["post-4051","post","type-post","status-publish","format-standard","hentry","category-noticias","tag-infobae","tag-informacion-general","tag-noticias","tag-novedades"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Los antecedentes familiares juegan un papel en el riesgo gen\u00e9tico de c\u00e1ncer de mama, seg\u00fan los investigadores - HIOX<\/title>\n<meta name=\"description\" content=\"Los antecedentes familiares juegan un papel en el riesgo gen\u00e9tico de c\u00e1ncer de mama, seg\u00fan los investigadores. 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